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Within a current review, we reported the identification as well as the characterization of a fresh atypical opioid receptor with one of a kind adverse regulatory Houses in direction of opioid peptides.1 Our effects confirmed that ACKR3/CXCR7, hitherto often known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, can also be a wide